J.M. - 78y.o.WM, retired, Type 2 DM, CAD, following bypass graft fem to ant. Tibial art developed total occlusion from lower leg including ankle and foot. Skin pale, cold, mottled. No pulses in foot. After 3 treatments with CB foot resumed pink color, skin warm, palpable pulses. Remains functioning well.

L.O. - 77 y.o. WF, obese, found at home in coma, multiple leg wounds, deep, foul smelling, admitted with keto-acidosis, bs -700. Scheduled for AKA amputation on left, BKA on rt. Surgeon reluctantly agree to postpone amputations. Magots applied. CB treatment - healed with no need for amputation. S. - with shower of chol emboli. Treatment reversed necrotic toes changes.

R.C. - limousine driver, type 2 DM, .admitted with severe cellulites, necrosis, needed partial middle toe amputation. Osteomyeklitis changes reported - scheduled for surgery - with treatments - healed and stays free of infection now for over 1 year. Fr. - Raynaud's finger amputation, treated in Mayo Clinic - after 5 years pain in fingers. Treated and released.

A.M. - 79 y.o. WF. With accidental fall- injured rt pretibial area. Deep hematoma, infected with ulceration.